Retroactivity: Paramount Powers and Contractual Changes

Retroactivity and administrative rulemaking.

Danforth, Retroactivity, and Federalism

Introduction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 426 I. A Very Brief Overview of Judicial Federalism in the Context of Criminal Process.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 428 II. Retroactivity Doctrine as Applied to Federal Constitutional New Rules.. . . . . . . . . . . . . . . . . . . . ...

Retroactivity and Crack Sentencing Reform

Modularity, Retroactivity, and Structural Identification

Many reverse-engineering techniques in systems biology rely upon data on steady-state (or dynamic) perturbations – obtained from siRNA, gene knockdown or overexpression, kinase and phosphatase inhibitors, or other interventions – in order to understand the interactions between different ‘modules’ in a network. This paper first reviews one popular such technique, introduced by the author and col...

ALDO-DHF & Paramount

1. ALDO-DHF STUDY – A NEW INDICATION FOR AN OLD DRUG? Results of the ALDOsterone receptor blockade in Diastolic Heart Failure (ALDO-DHF) were recently presented at the European Society of Cardiology (ESC) meeting in Munich [1]. The multicenter, double-blind randomized, placebo-controlled phase IIb mechanistic study was conducted to test the hypothesis that 12 months treatment with spironolacton...